MEDNAX Neonatal Nurse Practitioner (NNP) Practice Exam

The key idea is weight-based epinephrine dosing during neonatal resuscitation using a 1:10,000 solution. The dose is 0.01 mg/kg IV/IO every 3–5 minutes. For a 4 kg infant, that’s 0.04 mg per dose. Since 1:10,000 epinephrine is 0.1 mg per mL, the volume needed is 0.04 mg ÷ 0.1 mg/mL = 0.4 mL per dose. If you consider the typical dosing window across possible scenarios, that per-dose volume ranges from about 0.4 mL up to 1.2 mL (0.04–0.12 mg). Therefore, 0.4–1.2 mL is the correct range. The other volumes are not consistent with the weight-based calculation for this concentration.